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簡(jiǎn)要描述:This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant diseas
產(chǎn)品型號(hào):bsm-63284R
廠商性質(zhì):生產(chǎn)廠家
更新時(shí)間:2025-03-05
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